Rabbit Hemorrhagic Disease

Rabbit Hemorrhagic Disease

Rabbit sitting in lush green grass with a blurred forest background.

General Information

Species Name: Lagovirus spp.

Also Known As: RHDV

Pathogen Type: Virus

Organ System Affected: Liver, blood and clotting

Organisms Affected: Rabbits and hares

Transmissible to Humans: No


Why is it a Concern? 

RHDV is a highly infectious and highly lethal virus that affects rabbits and hares, domestic and wild. It is a persistent virus that can survive outside of a host for more than 3 months. Oftentimes, infected individuals may not show symptoms before death. RHDV has a mortality rate between 50-100%.


How is it Spread? 

RHDV is shed through all body secretions including saliva, urine, feces, and nasal discharge. It can be spread through direct contact between rabbits and hares and contact with contaminated surfaces. 

RHDV has been documented in the United States. Currently, there are no documented cases of RHDV in Nebraska.


Symptoms and Diagnosis

Incubation Period

Symptoms typically surface within 12-36 hours of infection. 

Forms

RHDV1 (RHDVa or classical RHDV) was the initial strain first detected in the 1980s. RHDV2 was first detected in 2010 and has displaced RHDV1 in many places due to its fast ability to spread. 

Symptoms

Symptoms of infected individuals may include: 

  • Sudden death

  • Nosebleeds or blood-stained nose

  • Seizures

  • Fever

  • Lethargy

  • Anorexia

  • Difficulty breathing

  • Loss of coordination

  • Red conjunctiva

Diagnosis

Diagnosis is confirmed post-mortem through necropsy and PCR testing. 


Prevention and Control

Vaccination

An experimental vaccination for use in domestic rabbits has been authorized for emergency use. Consult your veterinarian for more information and to determine if vaccination should be considered for your domestic rabbit. 

Maintain and Safe and Sanitary Environment for Your Rabbit

Rabbit owners should wash hands before and after handling rabbits and prevent unnecessary people from interacting with your rabbit. Avoid allowing your rabbit to run on the ground outdoors and only feed forage and pellets from unaffected states. House your rabbit indoors and quarantine new and returning rabbits for 30 days. 

Avoid Wildlife

Avoid areas where wild hare and rabbits frequent. Do not approach or touch wild rabbits and hare and do not move deceased bodies. 


What to Do if You Suspect RHDV

Domestic Rabbit Exposure

If your rabbit has been exposed to RHDV, is showing symptoms, or suddenly passed away, contact your veterinarian immediately. Isolate the rabbit, sanitize areas it inhabited, minimize handling, and wash your hands after interactions. 

Suspected Infected Wildlife

If you suspect wild rabbits or hares may be infected with RHDV, contact your nearest Nebraska Game and Parks office immediately. Do not attempt to approach or move the suspected infected rabbits and keep away from areas which they inhabit. 


References and More Information

American Veterinary Medical Association

Pennsylvania Game Commission

Cornell University College of Veterinary Medicine

USDA Animal and Plant Health Inspection Service

Nebraska Animal and Plant Health Protection Program

Nebraska Department of Agriculture

Nebraska Game and Parks Commission

Washington State Department of Agriculture